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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALR
All Species:
60.91
Human Site:
Y172
Identified Species:
89.33
UniProt:
P27797
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27797
NP_004334.1
417
48142
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110217
417
48095
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Dog
Lupus familis
XP_853393
417
48162
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Cat
Felis silvestris
Mouse
Mus musculus
P14211
416
47976
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Rat
Rattus norvegicus
P18418
416
47977
Y172
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514084
419
48477
Y173
D
D
E
F
T
H
L
Y
T
L
I
V
R
P
D
Chicken
Gallus gallus
XP_418262
419
48016
Y185
V
D
G
Y
T
H
L
Y
T
L
I
I
R
P
D
Frog
Xenopus laevis
NP_001080765
413
48503
Y173
D
D
S
F
T
H
L
Y
T
L
I
V
R
P
D
Zebra Danio
Brachydanio rerio
NP_956007
419
48936
Y173
D
D
E
Y
S
H
L
Y
T
L
I
V
N
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
Y172
D
D
V
Y
T
H
F
Y
T
L
I
V
R
P
D
Honey Bee
Apis mellifera
XP_392689
403
47156
Y171
D
D
I
Y
T
H
L
Y
T
L
I
V
K
P
D
Nematode Worm
Caenorhab. elegans
P27798
395
45598
Y167
S
D
E
L
T
H
L
Y
T
L
I
L
N
S
D
Sea Urchin
Strong. purpuratus
NP_999643
421
48804
Y171
D
D
E
F
T
H
L
Y
T
L
I
V
K
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
Y178
T
D
Q
L
T
H
V
Y
T
F
I
I
R
P
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38858
424
48138
Y175
T
D
Q
L
T
H
V
Y
T
F
I
L
R
P
D
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
Y204
D
T
S
Q
S
H
L
Y
T
L
I
I
D
E
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
94.9
N.A.
94.2
93.7
N.A.
84
59.6
78.1
74.4
N.A.
64.2
66.9
62.5
64.8
Protein Similarity:
100
N.A.
99.7
97.3
N.A.
97.5
97.3
N.A.
92.3
73.9
90.1
85.9
N.A.
76.5
77.6
75.3
79.3
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
73.3
93.3
80
N.A.
80
80
66.6
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
86.6
93.3
93.3
N.A.
86.6
93.3
73.3
93.3
Percent
Protein Identity:
N.A.
52.1
N.A.
51.4
26.1
N.A.
Protein Similarity:
N.A.
70
N.A.
68.1
40.8
N.A.
P-Site Identity:
N.A.
60
N.A.
60
46.6
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
94
0
0
0
0
0
0
0
0
0
0
7
0
94
% D
% Glu:
0
0
57
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
50
0
0
7
0
0
13
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
100
19
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
0
0
19
0
0
82
0
0
88
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
82
0
% P
% Gln:
0
0
13
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
69
0
0
% R
% Ser:
7
0
13
0
13
0
0
0
0
0
0
0
0
13
7
% S
% Thr:
13
7
0
0
88
0
0
0
100
0
0
0
0
0
0
% T
% Val:
7
0
7
0
0
0
13
0
0
0
0
69
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
25
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _